![]() Using PVP-I mouthwash six times/day and iota-carrageenan nasal spray three times/day for 5 to 6 days may reduce several subjective clinical symptoms. On the 8th day, there was a significant difference in symptoms between-group in dry cough (P=0.003), fever (P=0.024), and sore throat (P=0.001), and dysgeusia (P=0.042) on the 14th day. ![]() The five frequent symptoms were anosmia, dry cough, fever, slimed cough, and headache. (SARS-CoV-2 Infection) / Coronavirus Disease 2019 (COVID19) / COVID 19 / Corona Virus. The mean duration of PVP-I and IC used was 5.6 and 5.51 days, respectively. COVID - 19 Completed Phase Trials for iota-Carrageenan (DB15304). Male, 19-30 y.o were dominant in both groups. Chi- square was used to find the correlation among groups. Research Question: Can a nasal spray with Iota-Carrageenan be useful in the prophylaxis of COVID-19. Data collections were recorded at the beginning and end of observation for 17 subjective clinical symptoms. In vitro, I-C inhibits SARS-CoV-2 infection in cell culture. Marinomed Biotech AG, a globally operating biopharmaceutical company, is pleased to announce today that the Swansea University Medical School plans a clinical trial with Iota-/kappa-carrageenan. Eighty-nine subjects who received standard drug of COVID-19 were then divided into Group-A that received PVP-I for 14 days, IC for seven days, and Group-B, who did not receive. Recruitment of subjects obtains from those who fulfilled the inclusion criteria under informed consent. A single-blind randomized clinical trial was done in Wisma Atlet emergency hospital. Aim: To evaluate subjective clinical symptoms in COVID-19 patients after using PVP-I 1% mouthwash and IC nasal spray. Clinical trials of the above regimes on COVID-19 patients have never been carried out. Viral reservoirs are found at naso-oropharyngeal areas and challenge the dentist to reduce the virus using antiseptics, such as PVP-I and Iota-carrageenan (IC). Title : PVP-I and Iota-Carrageenan Improve Subjective Clinical Symptoms In COVID-19 Emergency Hospital Wisma Atlet, Indonesia: A Single-Blind Randomized Clinical Trial Abstract :ĬOVID-19 caused various symptomatic manifestations in humans.
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